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Headquartered in Menlo Park, Ionpath Inc. delivers high-definition spatial proteomics, revolutionizing
tissue imaging and analysis to accelerate discovery and improve human health. Ionpath’s MIBI™
(multiplexed ion beam imaging) Platform breaks through the limitations of traditional IHC, enabling
deep understanding of the tissue microenvironment with highly multiplexed quantitative single-cell
analysis. With MIBI technology and the expertise of world class pathology and data science teams,
Ionpath provides actionable insights to translational and clinical researchers at leading pharma, biotech,
and research organizations in immuno-oncology, immunology, neuroscience and infectious disease
research.
About the role
Ionpath seeks an experienced electrical design engineer to design, develop, integrate, troubleshoot, test
and document complex analog and digital circuits that may include RF, low noise amplifier circuits,
scanning and HV electronics for charged particle systems, and instrument control HW and
FW/embedded SW.
About you: You are a seasoned, proactive and hands-on electrical design engineer with experience with
high performance complex commercial products, ideally including sensitive high speed signal detection
and processing, and high voltage. Life science capital equipment experience is a huge plus, where you
have worked within a formal design controls environment. You are creative as well as detail oriented.
You seek fast solutions, while being disciplined about meeting requirements. You thrive in a startup
environment where you get to work with smart people from a wide variety of disciplines, working with
them to develop system requirements and architectures. You are a team player who can think
independently and work without regular direct supervision. You are a driver, not a passenger.
Job Responsibilities:
Conceive, design, build, and evaluate:
Signal amplifier and pulse detection electronics for particle detectors,
Control and HV electronics for charged particle sources, optical columns, spectrometers, and detectors,
Instrument control HW and FW, based on e.g. FPGA, PLC, microcontrollers or SBC.
Develop designs using best practices including design for manufacture (DFM) and design for service
(DFS).
Create documentation including schematics, PCB layouts, PCB fabrication files, test plans, test reports,
and design reviews.
Source and procure prototype parts and components, work with 3 rd party electronic manufacturers to
complete prototype builds
Support the release of production worthy design files.
Transfer engineering assembly and test methods to manufacturing in preparation for production.
Debug functionality and reliability and iterate design to correct issues
Develop and execute formal verification tests for electronic HW
Collaborate with systems engineers to define architectures and requirements at the system level and for
various electrical, power and automation subsystems, to ensure the overall MIBIscope system meets
feature, performance, cost and reliability requirements.
Rapidly prototype sub-system or module proof of concept experiments to quantitatively compare to
predicted performance.
Conceive, drive and release to manufacturing rapid continuous improvement projects (CIPs) to enhance
the usability, performance and/or reliability of existing products.
Secondary responsibilities:
Identify strategic suppliers, partners and consultants, and manage co-development projects.
Minimum qualifications and experience:
Minimum 10+ years of experience designing, fabricating, testing and transferring to production electrical
assemblies and subsystems for complex, high performance instruments or capital equipment. Have
been lead design EE for multiple systems or major, complex subsystems transferred to production.
Minimum 3+ years of experience with two or more of the following:
High voltage power supplies and electronics (500 V to 5 kV) including precision ramp generators and
high speed pulsers.
High voltage power supplies (to 30 kV)
High speed (to 2 GHz), low noise analog electronics, including particle detector (e.g. PMT or APD)
preamplifiers.
Time of flight spectroscopy electronics, or similar.
Firmware, embedded software and communications protocols for instrument control.
Proficient with ECAD and circuit modeling; Altium experience strongly preferred.
Ability to use programming or scripting languages (e.g. Matlab, Python, Jupyter notebooks) for data
analysis and/or automated test.
Ability to create and adhere to project schedules.
Highly self-motivated individual with conscientious work habits. Articulate, and able to collaborate
effectively with other members of the project team.
Education: Bachelor’s degree in Electrical Engineering. Masters or PhD is preferred. A degree in another
technical field with relevant professional experience is also acceptable.
Desired qualifications and experience:
Excellent presentation and written communication skills.
Theoretical and experimental background, e.g. FEA or analytical analysis of E&M fields; hand on
measurement of system performance, such as SNR.
Project management experience.
Experience with life science equipment.
Experience with technical management of vendor/supplier development projects.
Experience with control systems/control loops.
Experience with vacuum systems.
Experience with regulatory compliance, e.g. ISO 13485 and/or IEC 61010
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